| Geno
|
Mag
|
Summary
|
| (A;A)
|
1.5
|
2x higher risk for melanoma
|
| (A;C)
|
1.5
|
1.5x higher risk for melanoma
|
| (C;C)
|
0
|
common
|
rs4785763 is a SNP near the MC1R gene, which encodes the melanocortin 1 receptor.
| GWAS snp
|
| PMID
|
[PMID 19578364 ]
|
| Trait
|
Melanoma
|
| Title
|
Genome-wide association study identifies three loci associated with melanoma risk
|
| Risk Allele
|
A
|
| P-val
|
6E-22
|
| Odds Ratio
|
1.36 [1.28-1.45]
|
[PMID 24270849] rs4785763 was found to be associated with melanoma based on a study by the eMERGE network in which electronic medical records were searched to find clinical associations associated with selected SNPs.
[PMID 18483556] A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
[PMID 19340012] Genome-wide association study of tanning phenotype in a population of European ancestry.
]
