rs4112788
| Orientation | minus |
| Stabilized | minus |
| Make rs4112788(C;C) |
| Make rs4112788(C;T) |
| Make rs4112788(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 152578800 |
| Gene | LCE3D |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4112788 |
| dbSNP (classic) | rs4112788 |
| ClinGen | rs4112788 |
| ebi | rs4112788 |
| HLI | rs4112788 |
| Exac | rs4112788 |
| Gnomad | rs4112788 |
| Varsome | rs4112788 |
| LitVar | rs4112788 |
| Map | rs4112788 |
| PheGenI | rs4112788 |
| Biobank | rs4112788 |
| 1000 genomes | rs4112788 |
| hgdp | rs4112788 |
| ensembl | rs4112788 |
| geneview | rs4112788 |
| scholar | rs4112788 |
| rs4112788 | |
| pharmgkb | rs4112788 |
| gwascentral | rs4112788 |
| openSNP | rs4112788 |
| 23andMe | rs4112788 |
| SNPshot | rs4112788 |
| SNPdbe | rs4112788 |
| MSV3d | rs4112788 |
| GWAS Ctlg | rs4112788 |
| GMAF | 0.332 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs4112788 tags the LCE3C_LCE3B deletion that has been associated with risk for psoriasis in a study of 2,800+ samples of European ancestry.
23andMe blog psoriasis Europeans
- rs4112788(G) 1.41x risk
[PMID 20213803] Deletion of the late cornified envelope genes, LCE3C and LCE3B, is associated with rheumatoid arthritis
[PMID 20331852
] Mutation analysis of the LCE3B/LCE3C genes in Psoriasis
[PMID 20643763] Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis
| GWAS snp | |
|---|---|
| PMID | [PMID 20953190]
|
| Trait | |
| Title | A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1 |
| Risk Allele | |
| P-val | 3E-10 |
| Odds Ratio | 1.2900 [1.19-1.40] |
[PMID 21400479] Deletion of the LCE3C and LCE3Bgenes is a susceptibility factor for psoriatic arthritis: A study in Spanish and Italian populations and meta-analysis
[PMID 21628307] Deletion of LCE3C_LCE3B is associated with rheumatoid arthritis and systemic lupus erythematosus in the Chinese Han population
[PMID 19169254] Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
[PMID 19439430] Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients.
[PMID 19638187] Genetic susceptibility to psoriasis: an emerging picture.
[PMID 21509048] Deletion of the late cornified envelope genes LCE3C and LCE3B is associated with psoriasis in a Chinese population.
[PMID 23594316] Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders
[PMID 24566688] Deletion of late cornified envelope genes, LCE3C_LCE3B-del, is not associated with psoriatic arthritis in Tunisian patients
