rs3889728

minus

Geno	Mag	Summary
(A;A)		increased risk for preeclampsia
(A;G)		increased risk for preeclamppsia
(G;G)		normal risk

Reference

GRCh38 38.1/141

Chromosome

1

Position

230713085

Gene

AGT

is a	snp
is	mentioned by
dbSNP	rs3889728
dbSNP (classic)	rs3889728
ClinGen	rs3889728
ebi	rs3889728
HLI	rs3889728
Exac	rs3889728
Gnomad	rs3889728
Varsome	rs3889728
LitVar	rs3889728
Map	rs3889728
PheGenI	rs3889728
Biobank	rs3889728
1000 genomes	rs3889728
hgdp	rs3889728
ensembl	rs3889728
geneview	rs3889728
scholar	rs3889728
google	rs3889728
pharmgkb	rs3889728
gwascentral	rs3889728
openSNP	rs3889728
23andMe	rs3889728
SNPshot	rs3889728
SNPdbe	rs3889728
MSV3d	rs3889728
GWAS Ctlg	rs3889728

GMAF

0.3104

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

rs3889728 is a SNP in the AGT gene that, at least when part of a haplotype, has been associated with increased risk for developing pre-eclampsia, but it was not reported to have the most influence of the 3 SNPs in the haplotype. The 2.1 fold increased risk (CI: 1.4-3.4, p=0.0008) for pre-eclampsia was reported for haplotype rs3889728(A)-rs4762(T)-rs699(C).[PMID 14638622]

[PMID 24978482] Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: Interplay with hypertension and intakes of sodium, potassium and fluid

[PMID 31337952 ] A Prediction Model of Essential Hypertension Based on Genetic and Environmental Risk Factors in Northern Han Chinese.