|| 0.4x decreased risk of breast cancer
|?|| (A;A) (A;G) (G;G) ||28|
is a SNP in the V-set domain containing T cell activation inhibitor 1 VTCN1
gene, which is also known as B7-H4.
A study of 500 Chinese Han women with breast cancer (and an equal number of matched controls) concluded that the rs3738414(A;A) genotype showed a significantly decreased risk of breast cancer (odds ratio 0.412, CI: 0.203-0.835).[PMID 19903360]
[PMID 24125968] An investigation of the effects of FGFR2 and B7-H4 polymorphisms in breast cancer