|| common in clinvar
is a SNP in the 3' UTR of the alpha-synuclein SNCA
gene. It has been associated in some studies, and not others, with Parkinson's disease.
[PMID 20478361] A study of 330 Chinese with Parkinson's found no association with rs356165 and risk for Parkinson's.
|?|| (A;A) (A;G) (G;G) ||28|
] Multiple alpha-synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population.
[PMID 22076805] A Search for SNCA 3' UTR Variants Identified SNP rs356165 as a Determinant of Disease Risk and Onset Age in Parkinson's Disease
[PMID 22451204] Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2
[PMID 15637659] Linkage disequilibrium patterns and tagSNP transferability among European populations.
[PMID 17531291] Familial genes in sporadic disease: common variants of alpha-synuclein gene associate with Parkinson's disease.
[PMID 17872362] alpha-Synuclein and Parkinson disease susceptibility.
[PMID 19063963] Genetic susceptibility in Parkinson's disease.
[PMID 19771175] Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.
[PMID 19890971] Alpha-synuclein polymorphisms are associated with Parkinson's disease in a Saskatchewan population.
[PMID 22291217] An evaluation of the impact of MAPT, SNCA and APOE on the burden of Alzheimer's and Lewy body pathology.