rs3176336
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common/normal |
| (A;T) | ? | |
| (T;T) | 1.2 | Slightly higher (1.25x) higher risk for breast cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 6 |
| Position | 36681039 |
| Gene | CDKN1A |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3176336 |
| dbSNP (classic) | rs3176336 |
| ClinGen | rs3176336 |
| ebi | rs3176336 |
| HLI | rs3176336 |
| Exac | rs3176336 |
| Gnomad | rs3176336 |
| Varsome | rs3176336 |
| LitVar | rs3176336 |
| Map | rs3176336 |
| PheGenI | rs3176336 |
| Biobank | rs3176336 |
| 1000 genomes | rs3176336 |
| hgdp | rs3176336 |
| ensembl | rs3176336 |
| geneview | rs3176336 |
| scholar | rs3176336 |
| rs3176336 | |
| pharmgkb | rs3176336 |
| gwascentral | rs3176336 |
| openSNP | rs3176336 |
| 23andMe | rs3176336 |
| 23andMe all | rs3176336 |
| SNPshot | rs3176336 |
| SNPdbe | rs3176336 |
| MSV3d | rs3176336 |
| GWAS Ctlg | rs3176336 |
| GMAF | 0.3797 |
| Max Magnitude | 1.2 |
rs3176336 shows an association with breast cancer in a British study involving ~2300 patients. The odds ratio for the (T;T) vs (A;A) homozygotes is 1.25 (CI: 1.11-1.42, p=0.0026).[PMID 18174243
]
[PMID 17459456] A common variant of the p16(INK4a) genetic region is associated with physical function in older people.
[PMID 19124506] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
[PMID 19258477] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.
