rs3176336
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 0 | common/normal |
(A;T) | ? | |
(T;T) | 1.2 | Slightly higher (1.25x) higher risk for breast cancer |
Reference | GRCh38 38.1/141 |
Chromosome | 6 |
Position | 36681039 |
Gene | CDKN1A |
is a | snp |
is | mentioned by |
dbSNP | rs3176336 |
dbSNP (classic) | rs3176336 |
ClinGen | rs3176336 |
ebi | rs3176336 |
HLI | rs3176336 |
Exac | rs3176336 |
Gnomad | rs3176336 |
Varsome | rs3176336 |
LitVar | rs3176336 |
Map | rs3176336 |
PheGenI | rs3176336 |
Biobank | rs3176336 |
1000 genomes | rs3176336 |
hgdp | rs3176336 |
ensembl | rs3176336 |
geneview | rs3176336 |
scholar | rs3176336 |
rs3176336 | |
pharmgkb | rs3176336 |
gwascentral | rs3176336 |
openSNP | rs3176336 |
23andMe | rs3176336 |
23andMe all | rs3176336 |
SNPshot | rs3176336 |
SNPdbe | rs3176336 |
MSV3d | rs3176336 |
GWAS Ctlg | rs3176336 |
GMAF | 0.3797 |
Max Magnitude | 1.2 |
rs3176336 shows an association with breast cancer in a British study involving ~2300 patients. The odds ratio for the (T;T) vs (A;A) homozygotes is 1.25 (CI: 1.11-1.42, p=0.0026).[PMID 18174243]
[PMID 17459456] A common variant of the p16(INK4a) genetic region is associated with physical function in older people.
[PMID 19124506] Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer.
[PMID 19258477] Candidate gene analysis using imputed genotypes: cell cycle single-nucleotide polymorphisms and ovarian cancer risk.