|| normal risk for infertility in Chinese men
|| 1.36 slightly higher risk for infertility in Chinese men
|| >1.36 higher risk for infertility in Chinese men
is a SNP in the HLA gene region. It has been associated with slightly (~30%) higher risk for azoospermia (lack of sperm) and thus male infertility
in both Chinese and Japanese men.[PMID 22541561
|?|| (A;A) (A;C) (C;C) ||28|
] HLA-DPB1*04:01 allele is associated with non-obstructive azoospermia in Japanese patients
[PMID 19846760] Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases.
[PMID 22541561] A genome-wide association study reveals that variants within the HLA region are associated with risk for nonobstructive azoospermia.