|?|| (A;A) (A;G) (G;G) ||28|
both significantly associated with type 1 diabetes
odds ratio 1.37 and 1.28. A joint analysis revealed that rs3087243
, and rs2903692
, but not INS rs689
, were significant risk factors for the cooccurrence of AITD
[PMID 19317741] Autoimmune disease association signals in CIITA and KIAA0350 are not involved in celiac disease susceptibility
|Desc||DIABETES MELLITUS, INSULIN-DEPENDENT; IDDM|
|Desc||C-TYPE LECTIN DOMAIN FAMILY 16, MEMBER A; CLEC16A|
] Chromosomal region 16p13: further evidence of increased predisposition to immune diseases.
[PMID 19337309] Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patients.
[PMID 20369022] Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
|| Insufficiently evaluated pathogenic