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rs2848745

From SNPedia

Orientationplus
Stabilizedplus
Make rs2848745(C;C)
Make rs2848745(C;G)
Make rs2848745(G;G)
ReferenceGRCh38 38.1/141
Chromosome18
Position41477761
is asnp
is mentioned by
dbSNPrs2848745
dbSNP (old)rs2848745
ClinGenrs2848745
ebirs2848745
HLIrs2848745
Exacrs2848745
Varsomers2848745
Maprs2848745
PheGenIrs2848745
Biobankrs2848745
1000 genomesrs2848745
hgdprs2848745
ensemblrs2848745
gopubmedrs2848745
geneviewrs2848745
scholarrs2848745
googlers2848745
pharmgkbrs2848745
gwascentralrs2848745
openSNPrs2848745
23andMers2848745
23andMe allrs2848745
SNP Nexus

SNPshotrs2848745
SNPdbers2848745
MSV3drs2848745
GWAS Ctlgrs2848745
GMAF0.4288
Max Magnitude
? (C;C) (C;G) (G;G) 28
This SNP was identified as a "core" SNP helping to define one (of nine total) runs of homozygosity (ROH) potentially associated with increased risk for schizophrenia. Each region consists of at least 100 consecutive SNPs, generally spanning 500KB or more, for which both chromosomes in an individual were homozygous. The overall odds ratio for schizophrenia associated with inheriting 1, 2, or 3 of these 9 ROHs was calculated to be 3.3, 5.4, or 24, respectively, with 95% confidence intervals of (1.9-5.7), (3.7-16.1), and (6.9-83.9), respectively.[PMID 18077426OA-icon.png]

This particular SNP, rs2848745, was deemed to be the core SNP of a region on chromosome 18 with 119 SNPs spanning 597KB from 18:37022928 to 18:37619977 (build 35). Potentially independent of the ROH, the risk allele for this SNP in the orientation as displayed in HapMap v21a is (C).[PMID 18077426OA-icon.png]