||1.5x risk of high blood pressure
||1.1x risk of high blood pressure
rs2820037 has been reported in a large study to be associated with high blood pressure.
The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.54 (CI 1.03-2.31), and for homozygotes, 1.09 (CI 0.74-1.62). [PMID 17554300]
[PMID 18523456] Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program.
[PMID 20018036] Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.
[PMID 23438931] Relationships between selected gene polymorphisms and blood pressure sensitivity to weight loss in elderly persons with hypertension.