rs2745557
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | autism risk? | |
| (A;G) | autism risk? | |
| (G;G) | 0 | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 186680089 |
| Gene | PACERR, PTGS2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2745557 |
| dbSNP (classic) | rs2745557 |
| ClinGen | rs2745557 |
| ebi | rs2745557 |
| HLI | rs2745557 |
| Exac | rs2745557 |
| Gnomad | rs2745557 |
| Varsome | rs2745557 |
| LitVar | rs2745557 |
| Map | rs2745557 |
| PheGenI | rs2745557 |
| Biobank | rs2745557 |
| 1000 genomes | rs2745557 |
| hgdp | rs2745557 |
| ensembl | rs2745557 |
| geneview | rs2745557 |
| scholar | rs2745557 |
| rs2745557 | |
| pharmgkb | rs2745557 |
| gwascentral | rs2745557 |
| openSNP | rs2745557 |
| 23andMe | rs2745557 |
| SNPshot | rs2745557 |
| SNPdbe | rs2745557 |
| MSV3d | rs2745557 |
| GWAS Ctlg | rs2745557 |
| GMAF | 0.1387 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
A study of 151 Korean families reported that the rs2745557(A) allele of the PTGS2 gene, also known as cyclooxygenase-2 (Cox-2), was overtransmitted (p<0.01) in autism spectrum disorders.[PMID 18579107]
[PMID 19820421] The Effect of Genetic Polymorphisms of Cyclooxygenase 2 on Acute Pancreatitis in Turkey
[PMID 21705955] Cyclooxygenase-2 polymorphisms and pancreatic cancer susceptibility
[PMID 17609663
] COX2 genetic variation, NSAIDs, and advanced prostate cancer risk.
[PMID 18038187] Joint effect between regular use of non-steroidal anti-inflammatory drugs, variants in inflammatory genes and risk of lymphoma.
[PMID 18085997] Pyrosequencing of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance.
[PMID 18682823] Canadian Urological Association, 63rd Annual Meeting, Edmonton, AB, June 22-25, 2008.
[PMID 18768181] Association of polymorphisms in cyclooxygenase (COX)-2 with coronary and carotid calcium in the Diabetes Heart Study.
[PMID 19318492] Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk.
[PMID 19437564] No association between cyclooxygenase-2 and uridine diphosphate glucuronosyltransferase 1A6 genetic polymorphisms and colon cancer risk.
[PMID 19505919] Toll-like receptor signaling pathway variants and prostate cancer mortality.
[PMID 19560328] No association between the PPARG gene and schizophrenia in a British population.
