rs273897658

minus

Geno	Mag	Summary
(-;A)	6	BRCA1 variant considered pathogenic for breast cancer
(A;A)	0	common in clinvar

Make rs273897658(-;-)

Reference

GRCh38 38.1/142

Chromosome

17

Position

43094144

Gene

BRCA1

is a	snp
is	mentioned by
dbSNP	rs273897658
dbSNP (classic)	rs273897658
ClinGen	rs273897658
ebi	rs273897658
HLI	rs273897658
Exac	rs273897658
Gnomad	rs273897658
Varsome	rs273897658
LitVar	rs273897658
Map	rs273897658
PheGenI	rs273897658
Biobank	rs273897658
1000 genomes	rs273897658
hgdp	rs273897658
ensembl	rs273897658
geneview	rs273897658
scholar	rs273897658
google	rs273897658
pharmgkb	rs273897658
gwascentral	rs273897658
openSNP	rs273897658
23andMe	rs273897658
SNPshot	rs273897658
SNPdbe	rs273897658
MSV3d	rs273897658
GWAS Ctlg	rs273897658

Status

Merged into rs80357770

Max Magnitude

6

rs273897658, also known as 1506delA, c.1387_1387delA and p.Lys463=fs, is a variant in the BRCA1 gene considered pathogenic for breast cancer in ClinVar.

ClinVar
Risk
Alt
Reference	Rs273897658(A;A)
Significance	Pathogenic
Disease	Familial cancer of breast Breast-ovarian cancer
Variation	info
Gene	BRCA1
CLNDBN	Familial cancer of breast Breast-ovarian cancer, familial 1
Reversed	1
HGVS	NC_000017.10:g.41246158delT
CLNSRC	Breast Cancer Information Core (BRCA1)
CLNACC	RCV000047457.2, RCV000111604.4,