rs2515475
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | normal |
| (C;T) | 1.27x increased ARDS risk in critically ill patients | |
| (T;T) | 1.27x increased ARDS risk in critically ill patients |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 6530918 |
| Gene | ANGPT2, MCPH1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2515475 |
| dbSNP (classic) | rs2515475 |
| ClinGen | rs2515475 |
| ebi | rs2515475 |
| HLI | rs2515475 |
| Exac | rs2515475 |
| Gnomad | rs2515475 |
| Varsome | rs2515475 |
| LitVar | rs2515475 |
| Map | rs2515475 |
| PheGenI | rs2515475 |
| Biobank | rs2515475 |
| 1000 genomes | rs2515475 |
| hgdp | rs2515475 |
| ensembl | rs2515475 |
| geneview | rs2515475 |
| scholar | rs2515475 |
| rs2515475 | |
| pharmgkb | rs2515475 |
| gwascentral | rs2515475 |
| openSNP | rs2515475 |
| 23andMe | rs2515475 |
| SNPshot | rs2515475 |
| SNPdbe | rs2515475 |
| MSV3d | rs2515475 |
| GWAS Ctlg | rs2515475 |
| GMAF | 0.1621 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs2515475 is a SNP in the angiopoietin 2 ANGPT2 gene.
A study of 1,529 critically ill patients with risk factors for acute respiratory distress syndrome (ARDS), of whom 449 did develop ARDS and 1,080 did not, found that carriers of a rs2515475(T) allele were at higher risk for ARDS (adjusted odds ratio 1.28, p = 0.042). This risk was higher (odds ratio 1.79) in patients with extrapulmonary injuries.[PMID 19271210
]
