| Increased risk for Crohn's disease |
| GWAS snp
|
| PMID
|
[PMID 20570966 ]
|
| Trait
|
Crohn's disease
|
| Title
|
Fucosyltransferase 2(FUT2) Non-Secretor Status is associated with Crohn's Disease
|
| Risk Allele
|
|
| P-val
|
6E-8
|
| Odds Ratio
|
1.37 [1.22-1.53]
|
DeCode reports that rs2301436 is associated with susceptibility to Crohn's disease. [PMID 18587394]
[PMID 22269120] Investigation of JAK2, STAT3 and CCR6 polymorphisms and their gene-gene interactions in inflammatory bowel disease
[PMID 19557189] Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions.
[PMID 20018022] Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data.
[PMID 21304891] A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
[PMID 21763254] Polymorphisms in CCR6 are associated with chronic graft-versus-host disease and invasive fungal disease in matched-related hematopoietic stem cell transplantation.
[PMID 21873313] There is no association of CCR6 polymorphisms with susceptibility to Behcet's disease in two Chinese Han populations.
[PMID 22922229] Seven newly identified loci for autoimmune thyroid disease.
[PMID 29228965] Genetic polymorphism in ATG16L1 gene is associated with adalimumab use in inflammatory bowel disease.
]
