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rs2273504

From SNPedia

Orientationplus
Stabilizedplus
Make rs2273504(A;A)
Make rs2273504(A;G)
Make rs2273504(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position63356709
GeneCHRNA4
is asnp
is mentioned by
dbSNPrs2273504
dbSNP (classic)rs2273504
ClinGenrs2273504
ebirs2273504
HLIrs2273504
Exacrs2273504
Gnomadrs2273504
Varsomers2273504
LitVarrs2273504
Maprs2273504
PheGenIrs2273504
Biobankrs2273504
1000 genomesrs2273504
hgdprs2273504
ensemblrs2273504
geneviewrs2273504
scholarrs2273504
googlers2273504
pharmgkbrs2273504
gwascentralrs2273504
openSNPrs2273504
23andMers2273504
SNPshotrs2273504
SNPdbers2273504
MSV3drs2273504
GWAS Ctlgrs2273504
GMAF0.2392
Max Magnitude0
OMIM118504
DescCHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 4; CHRNA4
Variant
Relatedalso


[PMID 19482438] Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence


[PMID 15154117OA-icon.png] A common haplotype of the nicotine acetylcholine receptor alpha 4 subunit gene is associated with vulnerability to nicotine addiction in men.


[PMID 17135278OA-icon.png] Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs.


[PMID 17503330OA-icon.png] A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence.


[PMID 18534558OA-icon.png] Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence.


[PMID 18571741OA-icon.png] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.


[PMID 18618000OA-icon.png] A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction.


[PMID 19259974OA-icon.png] Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.


[PMID 22180580] Association Between Nicotinic Acetylcholine Receptor Single Nucleotide Polymorphisms and Smoking Cessation.