|| 2.03x risk of osteoarthritis
|| 1.48x risk of osteoarthritis
|| No increased risk of osteoarthritis
|?|| (C;C) (C;G) (G;G) ||28|
] Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis. Heterozygous odds ratio 1.481 (1.201–1.827) p<0.001; Homozygous minor odds ratio 2.038 (0.693–5.992) p = 0.187
[PMID 20111910] Sterol regulatory element-binding transcription factor (SREBF)-2, SREBF cleavage-activating protein (SCAP), and premature coronary artery disease in a Chinese population
[PMID 19116028] Expression of sterol regulatory element-binding transcription factor (SREBF) 2 and SREBF cleavage-activating protein (SCAP) in human atheroma and the association of their allelic variants with sudden cardiac death.
[PMID 19740467] Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.
|| not reviewed
|| Insufficiently evaluated not reviewed
[PMID 24992162] Relationship of SREBP-2 rs2228314 G>C Polymorphism with Nonalcoholic Fatty Liver Disease in a Han Chinese Population
[PMID 25005769] Association Between Single Nucleotide Polymorphisms of Sterol Regulatory Element Binding Protein-2 and Liver X Receptor α Gene and Risk of Polycystic Ovary Syndrome in a Chinese Han Population