rs2227692
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | common in complete genomics |
| (C;T) | 1.6 | 1.6x higher risk for diffuse gastric cancer |
| (T;T) | 1.6 | 1.6x higher risk for diffuse gastric cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 101135963 |
| Gene | SERPINE1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2227692 |
| dbSNP (classic) | rs2227692 |
| ClinGen | rs2227692 |
| ebi | rs2227692 |
| HLI | rs2227692 |
| Exac | rs2227692 |
| Gnomad | rs2227692 |
| Varsome | rs2227692 |
| LitVar | rs2227692 |
| Map | rs2227692 |
| PheGenI | rs2227692 |
| Biobank | rs2227692 |
| 1000 genomes | rs2227692 |
| hgdp | rs2227692 |
| ensembl | rs2227692 |
| geneview | rs2227692 |
| scholar | rs2227692 |
| rs2227692 | |
| pharmgkb | rs2227692 |
| gwascentral | rs2227692 |
| openSNP | rs2227692 |
| 23andMe | rs2227692 |
| SNPshot | rs2227692 |
| SNPdbe | rs2227692 |
| MSV3d | rs2227692 |
| GWAS Ctlg | rs2227692 |
| GMAF | 0.2117 |
| Max Magnitude | 1.6 |
rs2227692, also known as c.1162+162C>T, is a SNP in the SERPINE1 gene.
A study of 612 Korean patients with gastric cancer concluded that the rs2227692 C/T and T/T genotypes had 1.6x greater risk for diffuse gastric cancer than the C/C genotype (p = .00084).[PMID 20549826]
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 27510778] [Association of single nucleotide polymorphisms in PAI-1 with breast cancer susceptibility and prognosis].
