rs1990622
| Orientation | minus |
| Stabilized | minus |
| Make rs1990622(C;C) |
| Make rs1990622(C;T) |
| Make rs1990622(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 7 |
| Position | 12244161 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1990622 |
| dbSNP (classic) | rs1990622 |
| ClinGen | rs1990622 |
| ebi | rs1990622 |
| HLI | rs1990622 |
| Exac | rs1990622 |
| Gnomad | rs1990622 |
| Varsome | rs1990622 |
| LitVar | rs1990622 |
| Map | rs1990622 |
| PheGenI | rs1990622 |
| Biobank | rs1990622 |
| 1000 genomes | rs1990622 |
| hgdp | rs1990622 |
| ensembl | rs1990622 |
| geneview | rs1990622 |
| scholar | rs1990622 |
| rs1990622 | |
| pharmgkb | rs1990622 |
| gwascentral | rs1990622 |
| openSNP | rs1990622 |
| 23andMe | rs1990622 |
| SNPshot | rs1990622 |
| SNPdbe | rs1990622 |
| MSV3d | rs1990622 |
| GWAS Ctlg | rs1990622 |
| GMAF | 0.4389 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
[PMID 24385136
] TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia
[PMID 24343233] Effect of TMEM106B polymorphism on functional network connectivity in asymptomatic GRN mutation carriers.
[PMID 24166182] TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in Han Chinese
[PMID 23742080] TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia
[PMID 21354975] TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort.
[PMID 21220649] Association of TMEM106B Gene Polymorphism With Age at Onset in Granulin Mutation Carriers and Plasma Granulin Protein Levels
[PMID 21178100] TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers
[PMID 20154673] Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
[PMID 24770881] ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology
[PMID 25096617] Association of TMEM106B rs1990622 Marker and Frontotemporal Dementia: Evidence for a Recessive Effect and Meta-Analysis
[PMID 25653292] The TMEM106B locus and TDP-43 pathology in older persons without FTLD
[PMID 25470345] Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology
[PMID 28189700] CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.
[PMID 28441426] Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
[PMID 30973966] TMEM106B Effect on Cognition in Parkinson's Disease and Frontotemporal Dementia.
