A study of ~15,000 Europeans found that increased circulating natriuretic peptide and thus lower blood pressure and hypertension were associated with SNPs rs17376328(A), rs5068, rs198358(C), rs632793(G)
[PMID 19219041]23andMe blog
[PMID 19326473] Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.
[PMID 19439027] Dissecting complex traits: recent advances in hypertension genomics.
[PMID 20031578] Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
[PMID 20407391] Association of common variants in NPPA and NPPB with blood pressure does not translate into kidney damage in a general population study.
[PMID 21276798] Association of genetic variation in the natriuretic peptide system with cardiovascular outcomes.
[PMID 22504314] Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium.
[PMID 23315043] Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study
[PMID 30262711] Smoking modifies the effect of two independent SNPs rs5063 and rs198358 of NPPA on central obesity in the Chinese Han population.