||>1.59x risk of Type 2 diabetes
||1.59x risk of Type 2 diabetes
||No increased risk of Type 2 diabetes
[PMID 17893260] rs1143699, rs4807015, and rs1978237 confer an increased risk of developing type-2 diabetes. "SNP rs1143699 was associated with male T2D patients when compared with NGT controls (odds ratio; OR = 1.57; P = 0.029). SNP rs4807015 showed association with T2D patients when compared with NGT controls (OR = 1.32; P = 0.025). Finally, SNP rs1978237 was associated with T2D patients when compared with NGT controls (OR = 1.59; P = 0.002). Logistic regression analysis demonstrated that for SNP rs1143699 in men, C/C homozygosity conveys an increased risk of T2D (OR = 2.19; P = 0.035), while SNP rs4807015 was associated with an increased risk of T2D in both men and women (OR = 1.74; P = 0.029). SNP rs1978237 also demonstrated a risk of T2D in men and women (OR = 1.59; P = 0.026)." (Abstract)
[PMID 20111712] Risk of ovarian cancer and inherited variants in relapse-associated genes.