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rs1978237

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 1.6 >1.59x risk of Type 2 diabetes
(C;G) 1.6 1.59x risk of Type 2 diabetes
(G;G) 1 No increased risk of Type 2 diabetes
ReferenceGRCh38 38.1/141
Chromosome19
Position5209630
GenePTPRS
is asnp
is mentioned by
dbSNPrs1978237
dbSNP (old)rs1978237
ClinGenrs1978237
ebirs1978237
HLIrs1978237
Exacrs1978237
Gnomadrs1978237
Varsomers1978237
Maprs1978237
PheGenIrs1978237
Biobankrs1978237
1000 genomesrs1978237
hgdprs1978237
ensemblrs1978237
gopubmedrs1978237
geneviewrs1978237
scholarrs1978237
googlers1978237
pharmgkbrs1978237
gwascentralrs1978237
openSNPrs1978237
23andMers1978237
23andMe allrs1978237
SNP Nexus

SNPshotrs1978237
SNPdbers1978237
MSV3drs1978237
GWAS Ctlgrs1978237
GMAF0.2631
Max Magnitude1.6
? (C;C) (C;G) (G;G) 28
[PMID 17893260] rs1143699, rs4807015, and rs1978237 confer an increased risk of developing type-2 diabetes. "SNP rs1143699 was associated with male T2D patients when compared with NGT controls (odds ratio; OR = 1.57; P = 0.029). SNP rs4807015 showed association with T2D patients when compared with NGT controls (OR = 1.32; P = 0.025). Finally, SNP rs1978237 was associated with T2D patients when compared with NGT controls (OR = 1.59; P = 0.002). Logistic regression analysis demonstrated that for SNP rs1143699 in men, C/C homozygosity conveys an increased risk of T2D (OR = 2.19; P = 0.035), while SNP rs4807015 was associated with an increased risk of T2D in both men and women (OR = 1.74; P = 0.029). SNP rs1978237 also demonstrated a risk of T2D in men and women (OR = 1.59; P = 0.026)." (Abstract)


[PMID 20111712OA-icon.png] Risk of ovarian cancer and inherited variants in relapse-associated genes.

Neighborrs1143699
Distance1121