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rs1934951

From SNPedia

Orientationminus
Stabilizedminus
Make rs1934951(A;A)
Make rs1934951(A;G)
Make rs1934951(G;G)
ReferenceGRCh38 38.1/142
Chromosome10
Position95038791
GeneCYP2C8
is asnp
is mentioned by
dbSNPrs1934951
dbSNP (classic)rs1934951
ClinGenrs1934951
ebirs1934951
HLIrs1934951
Exacrs1934951
Gnomadrs1934951
Varsomers1934951
LitVarrs1934951
Maprs1934951
PheGenIrs1934951
Biobankrs1934951
1000 genomesrs1934951
hgdprs1934951
ensemblrs1934951
geneviewrs1934951
scholarrs1934951
googlers1934951
pharmgkbrs1934951
gwascentralrs1934951
openSNPrs1934951
23andMers1934951
SNPshotrs1934951
SNPdbers1934951
MSV3drs1934951
GWAS Ctlgrs1934951
GMAF0.2787
Max Magnitude0
? (A;A) (A;G) (G;G) 28


[PMID 18594024] (T;T) associated with a higher risk of osteonecrosis of the jaw in am small study of multiple myeloma patients under bisphosphonate therapy

GWAS
SNP rs1934951
PubMedID [PMID 18594024]
Condition Osteonecrosis of the jaw
Gene CYP2C8
Risk Allele T
pValue 1.00E-006
OR 12.75
95% CI 3.7-43.5


OMIM254500
DescMYELOMA, MULTIPLE
Variant
Relatedalso



[PMID 21151627OA-icon.png] A SNP in CYP2C8 is not associated with the development of bisphosphonate-related osteonecrosis of the jaw in men with castrate-resistant prostate cancer


[PMID 21685474OA-icon.png] CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma


[PMID 22339777] New approach to analyze genetic and clinical data in bisphosphonate-induced osteonecrosis of the jaw



[PMID 23171856] Association between CYP2C8 (rs1934951) Polymorphism and Bisphosphonate-Related Osteonecrosis of the Jaws in Patients on Bisphosphonate Therapy: A Meta-Analysis