|| common in complete genomics
|?|| (C;C) (C;T) (T;T) ||28|
| Disease Association
|| Defects in PLA2G7 are the cause of platelet-activating factor acetylhydrolase deficiency (PLA2G7 deficiency) (MIM:601690). It is a trait which is present in 27% of Japanese. It could have a significant physiologic effect in the presence of inflammatory bodily responses.
[PMID 18204052] Comprehensive genetic analysis of the platelet activating factor acetylhydrolase (PLA2G7) gene and cardiovascular disease in case-control and family datasets.
[PMID 20442857] Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.
|| not reviewed
|| Insufficiently evaluated not reviewed
[PMID 24732951] Lipoprotein-associated phospholipase A2 single-nucleotide polymorphisms and cardiovascular events in patients with coronary artery disease