||MAPT H1/H1 diplotype
||MAPT H1/H2 (heterozygous) diplotype
||MAPT H2/H2 diplotype
[PMID 21425343] replicates the association between rs1800547 and late-onset Parkinson's disease, calculating an odds ratio of 0.77 (CI: 0.66 - 0.88, p=3x10e-4) for the rarer rs1800547(G) allele among 1445 patients from northern Spain.
[PMID 18509094] significantly associated with parkinson's disease
|Desc||MICROTUBULE-ASSOCIATED PROTEIN TAU; MAPT|
[PMID 20951764] High cerebrospinal tau levels are associated with the rs242557 tau gene variant and low cerebrospinal beta-amyloid in Parkinson disease
[PMID 22104010] SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population
[PMID 19558713] Role of the H1 haplotype of microtubule-associated protein tau (MAPT) gene in Greek patients with Parkinson's disease.
[PMID 19763160] Genetic analysis of variation in human meiotic recombination.
[PMID 29084565] Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders.
[PMID 31866851] The MAPT H1 Haplotype Is a Risk Factor for Alzheimer's Disease in APOE ε4 Non-carriers.