|?|| (A;A) (A;C) (C;C) ||28|
] Role of glyoxalase I gene polymorphisms in late-onset epilepsy and drug-resistant epilepsy rs1781735 is a perfect proxy for rs1049346 with the G allele of rs1781735 corresponding to the C allele of rs1049346.The CC genotype of rs1049346 protects against late-onset epilepsy and drug resistant epilepsy (combined cohort, TT+TC/CC 2.645 p=0.000, and 3.049, p=0.001, respectively).
The presence of the TAC/AAT haplotypes (rs1130534-rs4746-rs1049346) may be used as a marker of predisposition to/protection against
drug resistant epilepsy (combined cohorts, p=0.010 and 0.000 respectively. ORs are not provided ).