rs17321515
| Orientation | plus |
| Stabilized | plus |
| Make rs17321515(A;A) |
| Make rs17321515(A;G) |
| Make rs17321515(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 8 |
| Position | 125474167 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs17321515 |
| dbSNP (classic) | rs17321515 |
| ClinGen | rs17321515 |
| ebi | rs17321515 |
| HLI | rs17321515 |
| Exac | rs17321515 |
| Gnomad | rs17321515 |
| Varsome | rs17321515 |
| LitVar | rs17321515 |
| Map | rs17321515 |
| PheGenI | rs17321515 |
| Biobank | rs17321515 |
| 1000 genomes | rs17321515 |
| hgdp | rs17321515 |
| ensembl | rs17321515 |
| geneview | rs17321515 |
| scholar | rs17321515 |
| rs17321515 | |
| pharmgkb | rs17321515 |
| gwascentral | rs17321515 |
| openSNP | rs17321515 |
| 23andMe | rs17321515 |
| SNPshot | rs17321515 |
| SNPdbe | rs17321515 |
| MSV3d | rs17321515 |
| GWAS Ctlg | rs17321515 |
| GMAF | 0.4917 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 18596051] rs17321515 influences severe hypertriglyceridemia. 132 patients of European ancestry with severe HTG (fasting plasma TG>10 mmol/L), and 351 matched normolipidemic controls
| GWAS | |
|---|---|
| SNP | rs17321515 |
| PubMedID | [PMID 18193043 ]
|
| Condition | Triglycerides |
| Gene | TRIB1 |
| Risk Allele | A |
| pValue | 7.00E-013 |
| OR | 6.42 |
| 95% CI | NR) mg/dl highe |
| GWAS snp | |
|---|---|
| PMID | [PMID 18193044]
|
| Trait | Triglycerides |
| Title | Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans |
| Risk Allele | A |
| P-val | 4.0000000000000003E-17 |
| Odds Ratio | 0.08 [0.06-0.10] % SD lower |
[PMID 19656773] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia
[PMID 20692138] Polymorphism at the TRIB1 gene modulates plasma lipid levels: Insight from the spanish familial hypercholesterolemia cohort study
[PMID 22145581] Association of the TRIB1 tribbles homolog 1 gene rs17321515 A>G polymorphism and serum lipid levels in the Mulao and Han populations
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 18987386] Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population.
[PMID 19060910] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
[PMID 19060911] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
[PMID 19185284] Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study.
[PMID 19197348] Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
[PMID 19304782] Admixture mapping of quantitative trait loci for blood lipids in African-Americans.
[PMID 19435741] Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
[PMID 20972250] Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.
[PMID 21691831] Triglyceride level-influencing functional variants of the ANGPTL3, CILP2, and TRIB1 loci in ischemic stroke.
[PMID 23596713] [SNP of rs17321515 homologous with Trib1 in Han population and its correlation with blood lipid]
| GWAS snp | |
|---|---|
| PMID | [PMID 24386095]
|
| Trait | Lipid traits |
| Title | A genome wide association study identifies common variants associated with lipid levels in the Chinese population. |
| Risk Allele | A |
| P-val | 8E-7 |
| Odds Ratio | .07 mmol/L increase |
[PMID 25986010] Association study of genetic variants at newly identified lipid gene TRIB1 with coronary heart disease in Chinese Han population
