|Individuals carrying the AA variant of the rs167771 SNP scored significantly higher on the IS-factor (resp U = 590, p < .01), indicating more rigid behavior than individuals carrying one or two copies of the minor G-allele.|
|?|| (A;A) (A;G) (G;G) ||28|
was significantly associated with autism
spectrum disorder in a study of 144 patients.
[PMID 19506579] G allele associated with increased extra-pyramidal symptom risk as a result of risperidone treatment in a study of 321 psychiatric inpatients (81 presenting with EPS and 189 without)
[PMID 21691864] Brief Report: The Dopamine-3-Receptor Gene (DRD3) is Associated with Specific Repetitive Behavior in Autism Spectrum Disorder (ASD)
[PMID 22309839] Association study of 45 candidate genes in nicotine dependence in Han Chinese
[PMID 18330705] Physiogenomic analysis of localized FMRI brain activity in schizophrenia.
[PMID 20148275] Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder.
[PMID 20619616] Searching for functional SNPs or rare variants in exonic regions of DRD3 in risperidone-treated patients.
[PMID 22397633] Neurotransmitter systems and neurotrophic factors in autism: association study of 37 genes suggests involvement of DDC.
|| Insufficiently evaluated pharmacogenetic
[PMID 25792691] DRD3 gene and striatum in autism spectrum disorder