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rs145946881

From SNPedia

Orientationplus
Stabilizedplus
Make rs145946881(C;C)
Make rs145946881(C;G)
Make rs145946881(G;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position135851176
GeneMCM6
is asnp
is mentioned by
dbSNPrs145946881
dbSNP (old)rs145946881
ClinGenrs145946881
ebirs145946881
HLIrs145946881
Exacrs145946881
Gnomadrs145946881
Varsomers145946881
Maprs145946881
PheGenIrs145946881
Biobankrs145946881
1000 genomesrs145946881
hgdprs145946881
ensemblrs145946881
gopubmedrs145946881
geneviewrs145946881
scholarrs145946881
googlers145946881
pharmgkbrs145946881
gwascentralrs145946881
openSNPrs145946881
23andMers145946881
23andMe allrs145946881
SNP Nexus

SNPshotrs145946881
SNPdbers145946881
MSV3drs145946881
GWAS Ctlgrs145946881
Max Magnitude
SNPs found in the introns of the MCM6 gene which turn out to have some control over the lactase LCT gene located many thousands of base pairs away include rs145946881, known as "G/C-14010", which appears to be associated with lactase persistence in sub-Saharan African populations. Two other nearby SNPs, rs41380347 "T/G(-13915)" and rs41525747 "C/G(-13907)", are also associated to a lesser degree. [PMID 17159977, PMID 23029545]
ClinVar
Risk rs145946881(G;G) rs145946881(T;T)
Alt rs145946881(G;G) rs145946881(T;T)
Reference rs145946881(C;C)
Significance Other
Disease Lactase persistence
Variation info
Gene MCM6
CLNDBN Lactase persistence
Reversed 0
HGVS NC_000002.11:g.136608746C>G
CLNSRC OMIM Allelic Variant
CLNACC RCV000008126.2,