|| ~2x increased risk for adult-onset asthma in Japanese populations
|?|| (A;A) (A;G) (G;G) ||28|
, also known as -603A>G, is a SNP in the promoter region of the coagulation factor III (aka thromboplastin or tissue factor) F3
Two unrelated Japanese populations both showed an association between rs1361600(G;G) and adult-onset asthma, with an odds ratio of ~2 (p=.02 or .06).[PMID 20150920]
[PMID 19583819] Tissue factor gene polymorphisms and haplotypes and the risk of ischemic vascular events: four studies and a meta-analysis.
[PMID 23274712] Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.
[PMID 25407675] Genetic variation in the tissue factor gene is associated with clinical outcome in severe sepsis patients