rs13420827
From SNPedia
Orientation | plus |
Stabilized | plus |
Make rs13420827(C;C) |
Make rs13420827(C;G) |
Make rs13420827(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 2 |
Position | 25231099 |
Gene | DNMT3A |
is a | snp |
is | mentioned by |
dbSNP | rs13420827 |
dbSNP (classic) | rs13420827 |
ClinGen | rs13420827 |
ebi | rs13420827 |
HLI | rs13420827 |
Exac | rs13420827 |
Gnomad | rs13420827 |
Varsome | rs13420827 |
LitVar | rs13420827 |
Map | rs13420827 |
PheGenI | rs13420827 |
Biobank | rs13420827 |
1000 genomes | rs13420827 |
hgdp | rs13420827 |
ensembl | rs13420827 |
geneview | rs13420827 |
scholar | rs13420827 |
rs13420827 | |
pharmgkb | rs13420827 |
gwascentral | rs13420827 |
openSNP | rs13420827 |
23andMe | rs13420827 |
SNPshot | rs13420827 |
SNPdbe | rs13420827 |
MSV3d | rs13420827 |
GWAS Ctlg | rs13420827 |
GMAF | 0.2144 |
Max Magnitude | 0 |
? | (C;C) (C;G) (G;G) | 28 |
---|---|---|
|
[PMID 18381459] 829 Caucasian cases with primary epithelial ovarian cancer and 941 frequency-matched unaffected controls Three SNPs in DNMT3A were associated with risk among multivitamin supplement users:
- 3' untranslated region (UTR) C>G (rs13420827: OR, 0.8; 95% CI, 0.6-1.0; P interaction = 0.006; FPRP = 0.54)
- intron 6 G>A (rs11887120: OR, 0.8; 95% CI, 0.7-1.0; P interaction = 0.007; FPRP = 0.57)
- intron 22 A>T (rs11695471: OR, 1.2; 95% CI, 1.0-1.5; P interaction = 0.01; FPRP = 0.66)
[PMID 20570913] Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium.