|?|| (A;A) (A;G) (G;G) ||28|
| Disease Association
|| Defects in WWOX may be involved in esophageal squamous cell carcinoma (ESCC) (MIM:133239).
[PMID 18674750] WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.
[PMID 19844255] Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.
[PMID 22693020] The polymorphisms and haplotypes of WWOX gene are associated with the risk of lung cancer in southern and eastern Chinese populations.
|| not reviewed
|| Insufficiently evaluated not reviewed
[PMID 26902998] The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysis.
[PMID 26929649] Association of polymorphisms in WWOX gene with risk and outcome of osteosarcoma in a sample of the young Chinese population.
[PMID 28426730] Functional genetic variant of WW domain-containing oxidoreductase (WWOX) gene is associated with hepatocellular carcinoma risk.