||4x more likely to have blond hair
||2x more likely to have blond hair
A 2007 study based on the Icelanders and Dutch concluded that individuals with an rs12821256(C) allele were ~2x fold more likely to have blond than brown hair color. The specific odds ratio claimed per (C) allele is 2.32, p = 5.5 x 10-14.[PMID 17952075]
[PMID 24880339] A molecular basis for classic blond hair color in Europeans: This article shows how changing just rs12821256 from (T) to (C) in a transgenic mouse leads to lighter hair color.
|Desc||SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 7; SHEP7|
[PMID 18483556] A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
[PMID 20042077] Genetic determinants of hair and eye colours in the Scottish and Danish populations.
[PMID 20585627] Web-based, participant-driven studies yield novel genetic associations for common traits.
||Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans.
||.18 [0.14-0.22] unit increase