|Trait||Body mass index|
|Title||Six new loci associated with body mass index highlight a neuronal influence on body weight regulation|
|Odds Ratio||0.19 [0.13-0.25] kg/m2|
[PMID 20061430] Obesity Susceptibility Genetic Variants Identified from Recent Genome-Wide Association Studies: Implications in a Chinese Population
|Title||Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index|
|Odds Ratio||0.18 [0.14-0.22] kg/m2 increase|
[PMID 20843981] Associations of six single nucleotide polymorphisms in obesity-related genes with BMI and risk of obesity in Chinese children[PMID 21796141] Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area
[PMID 21912638] Studies of metabolic phenotypic correlates of 15 obesity associated gene variants
[PMID 22083549] Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty
[PMID 19478790] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
[PMID 19526209] Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
[PMID 19553259] Common body mass index-associated variants confer risk of extreme obesity.
[PMID 19910641] Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus.
[PMID 19910938] Novel obesity risk loci do not determine distribution of body fat depots: a whole-body MRI/MRS study.
[PMID 20127379] From monogenic to polygenic obesity: recent advances.
[PMID 20520848] Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth.
[PMID 20712903] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
[PMID 20816195] Analyses of shared genetic factors between asthma and obesity in children.
[PMID 20824172] Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.
[PMID 21147891] Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study.
[PMID 21283731] FTO and MC4R gene variants are associated with obesity in polycystic ovary syndrome.
[PMID 21593506] Maternal and offspring adiposity-related genetic variants and gestational weight gain.
[PMID 22179955] Genetic predictors of weight loss and weight regain after intensive lifestyle modification, metformin treatment, or standard care in the Diabetes Prevention Program.
|qualified_impact||Insufficiently evaluated pathogenic|
[PMID 23431394] Rs4074134 near BDNF gene is associated with type 2 diabetes mellitus in chinese han population independently of body mass index
[PMID 23424664] Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children
[PMID 24269186] An obesity genetic risk score is associated with metabolic syndrome in Chinese children
|Trait||Body mass index|
|Title||Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.|
|Odds Ratio||1.16 [NR]|
[PMID 23471855] The genetics of childhood obesity and interaction with dietary macronutrients.
[PMID 23533005] Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder.
[PMID 23588626] Associations of obesity susceptibility loci with hypertension in Chinese children.
[PMID 25093408] Obesity-Related Genomic Loci Are Associated with Type 2 Diabetes in a Han Chinese Population
[PMID 25492288] [Impact of obesity-related gene polymorphism on risk of obesity and metabolic disorder in childhood]