rs10801935
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | normal | |
| (A;C) | normal | |
| (C;C) | 1.6 | 0.3x decreased risk of breast cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 1 |
| Position | 117179265 |
| Gene | VTCN1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10801935 |
| dbSNP (classic) | rs10801935 |
| ClinGen | rs10801935 |
| ebi | rs10801935 |
| HLI | rs10801935 |
| Exac | rs10801935 |
| Gnomad | rs10801935 |
| Varsome | rs10801935 |
| LitVar | rs10801935 |
| Map | rs10801935 |
| PheGenI | rs10801935 |
| Biobank | rs10801935 |
| 1000 genomes | rs10801935 |
| hgdp | rs10801935 |
| ensembl | rs10801935 |
| geneview | rs10801935 |
| scholar | rs10801935 |
| rs10801935 | |
| pharmgkb | rs10801935 |
| gwascentral | rs10801935 |
| openSNP | rs10801935 |
| 23andMe | rs10801935 |
| SNPshot | rs10801935 |
| SNPdbe | rs10801935 |
| MSV3d | rs10801935 |
| GWAS Ctlg | rs10801935 |
| GMAF | 0.3838 |
| Max Magnitude | 1.6 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
rs10801935 is a SNP in the V-set domain containing T cell activation inhibitor 1 VTCN1 gene, which is also known as B7-H4.
A study of 500 Chinese Han women with breast cancer (and an equal number of matched controls) concluded that the rs10801935(C;C) genotype showed a significantly decreased risk of breast cancer (odds ratio 0.328, CI: 0.145-0.739).[PMID 19903360
]
[PMID 24125968] An investigation of the effects of FGFR2 and B7-H4 polymorphisms in breast cancer
