|?|| (A;A) (A;C) (C;C) ||28|
is a SNP in an intron of the BNC2
gene on chromosome 9.
A GWAS study in Japanese and Han Chinese scoliosis patients found a significant (though small; odds ratio 1.21, p = 2.46 × 10e−13) association between rs10738445(A) and the disorder, and several lines of experiment evidence supported the hypothesis that increased BNC2 expression predisposes individuals to adolescent scoliosis (AIS).10.1016/j.ajhg.2015.06.012[PMID 26211971] A Functional SNP in BNC2 Is Associated with Adolescent Idiopathic Scoliosis
[PMID 28342042] Genetic variant of BNC2 gene is functionally associated with adolescent idiopathic scoliosis in Chinese population.