Have questions? Visit https://www.reddit.com/r/SNPedia

rs1059611

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0 common in clinvar
Make rs1059611(C;C)
Make rs1059611(C;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position19967052
GeneLPL
is asnp
is mentioned by
dbSNPrs1059611
dbSNP (old)rs1059611
ClinGenrs1059611
ebirs1059611
HLIrs1059611
Exacrs1059611
Varsomers1059611
Maprs1059611
PheGenIrs1059611
Biobankrs1059611
1000 genomesrs1059611
hgdprs1059611
ensemblrs1059611
gopubmedrs1059611
geneviewrs1059611
scholarrs1059611
googlers1059611
pharmgkbrs1059611
gwascentralrs1059611
openSNPrs1059611
23andMers1059611
23andMe allrs1059611
SNP Nexus

SNPshotrs1059611
SNPdbers1059611
MSV3drs1059611
GWAS Ctlgrs1059611
GMAF0.1235
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 23735640] Lipoprotein lipase gene polymorphism rs1059611 functionally influences serum lipid concentrations


[PMID 19148283OA-icon.png] Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.


[PMID 21840003] Genetic variations at the lipoprotein lipase gene influence plasma lipid concentrations and interact with plasma n-6 polyunsaturated fatty acids to modulate lipid metabolism.

GWAS snp
PMID [PMID 19936222OA-icon.png]
Trait Lipid metabolism phenotypes
Title Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
Risk Allele
P-val 2E-17
Odds Ratio .07 [NR] unit decrease


ClinVar
Risk rs1059611(C;C)
Alt rs1059611(C;C)
Reference Rs1059611(T;T)
Significance Probable-non-pathogenic
Disease Hyperlipoproteinemia
Variation info
Gene LPL
CLNDBN Hyperlipoproteinemia, type I
Reversed 0
HGVS NC_000008.10:g.19824563T>C
CLNSRC
CLNACC RCV000277765.1,