|(C;T)||2.5||2.8x increased risk for psoriasis|
|(T;T)||2.5||~4x increased risk for psoriasis|
|Gene||LOC105375015, LOC107984144, LOC107984145, LOC107984146|
[PMID 24270849] rs10484554 was found to be associated with psoriasis based on a study by the eMERGE network in which electronic medical records were searched to find what clinical associations were associated with selected SNPs.
|Title||Genomewide Association Study of an AIDS-Nonprogression Cohort Emphasizes the Role Played by HLA Genes (ANRS Genomewide Association Study 02).|
|Odds Ratio||NR NR|
|Title||A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1|
|Odds Ratio||4.6600 [4.23-5.13]|
[PMID 19107206] Distinct genetic loci control plasma HIV-RNA and cellular HIV-DNA levels in HIV-1 infection: the ANRS Genome Wide Association 01 study.
[PMID 19182814] New insights into the pathogenesis and genetics of psoriatic arthritis.
[PMID 19569043] Genome-wide association studies and the genetic dissection of complex traits.
[PMID 21221856] The search for host genetic factors of HIV/AIDS pathogenesis in the post-genome era: progress to date and new avenues for discovery.
[PMID 21253569] Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?
[PMID 21304891] A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.
[PMID 22474614] Host Genes Important to HIV Replication and Evolution.
[PMID 24566686] Human leukocyte antigen (HLA)-C polymorphisms are associated with a decreased risk of rheumatoid arthritis
[PMID 22931917] Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06.
[PMID 27073425] Candidate gene polymorphisms and risk of psoriasis: A pilot study
[PMID 33297781] HLA-Cw6 and other HLA-C alleles, as well as MICB-DT, DDX58 and TYK2 genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis.