Primaquine is used alone or with another medication to treat malaria (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death) and to prevent the disease from coming back in people that are infected with malaria. Primaquine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.MedlinePlus
The FDA-approved drug label for primaquine, which states that G6PD testing has to be performed before using the drug, and that it should not be prescribed for patients with severe G6PD deficiency; full details are here.
|Genotype/Genoset||Diplotype||Gene||Drug Use/Category/Class||Medical Field||Summary||Descriptive Sentence|
|gs309||WT/WT||G6PD||Anti-malarial||Infectious Disease||Normal Response Expected||You do not appear to carry any G6PD mutations linked to an unwanted side effect (hemolytic anemia).|
|gs307||Carrier||G6PD||Anti-malarial||Infectious Disease||Use with Caution||You carry a G6PD mutation that might lead to an unwanted side effect (hemolytic anemia) when taking primaquine; due to variable expression (i.e. in females), enzymatic testing for G6PD activity is advisable.|
|gs308||G6PD-deficient||G6PD||Anti-malarial||Infectious Disease||Avoid Use||You carry a G6PD mutation linked to an unwanted side effect (hemolytic anemia) when taking primaquine; primaquine should not be prescribed according to the FDA.|