Have questions? Visit https://www.reddit.com/r/SNPedia

NUDT15

From SNPedia
is agene
is mentioned by
ClinVarNUDT15
GeneCardsNUDT15
DiseasesNUDT15
wikipediaNUDT15
googleNUDT15
gopubmedNUDT15
EVSNUDT15
HEFalMpNUDT15
MyGene2NUDT15
23andMeNUDT15
# SNPs5
 Max MagnitudeChromosome positionSummary
rs116855232448,045,719
rs147390019048,045,720
rs186364861048,037,798
rs869320766048,037,801

Located on chromosome 13, the NUDT15 gene encodes the nudix hydrolase 15 enzyme. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia.GHR

Note that multiple pseudogenes of this gene have been identified, and technologies (such as DNA chips used by many direct-to-consumer companies) may not be accurate for this reason.