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MSH6

From SNPedia
is agene
is mentioned by
Full namemutS homolog 6 (E. coli)
EntrezGene2956
PheGenI2956
VariationViewer2956
ClinVarMSH6
GeneCardsMSH6
dbSNP2956
DiseasesMSH6
SADR2956
HugeNav2956
wikipediaMSH6
googleMSH6
gopubmedMSH6
EVSMSH6
HEFalMpMSH6
MyGene2MSH6
23andMeMSH6
UniProtP52701
EnsemblENSG00000116062
OMIM600678
# SNPs415
 Max MagnitudeChromosome positionSummary
i5037828
i5037835
i5037850
i5037852
i5037854
i5037857
i5037858
i5037859
i5037863
i5037864
i5037866
i5037872
i5037874
i5037877
i5037879
i5037880
i5037884
i5037888
i5037890
i5037891
i5037895
i5046060
i5046092
i5046093
i5046109
i5046129
i5046132
i5900868
i5900926
i5900962
i5901102
i5901124
i6015131
i723181
rs1042821047,783,349
rs1057517551047,798,891
rs1057517552047,803,462
rs1057517763047,804,920
rs1057517764047,805,634
rs1057520605047,798,839
rs1057524912047,791,068
rs1060502875047,791,108
rs1060502876047,800,718
rs1060502881047,805,638
rs1060502882047,801,132
rs1060502886047,799,798
rs1060502888047,798,856
rs1060502890047,800,974
rs1060502891047,803,500
rs1060502898047,806,858
... further results

MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. It is the homologue of the human "G/T binding protein," (GTBP) also called p160 or hMSH6 (human MSH6). The MSH6 protein is a member of the Mutator S (MutS) family of proteins that are involved in DNA damage repair. Defects in hMSH6 are associated with atypical hereditary nonpolyposis colorectal cancer (Lynch syndrome)not fulfilling the Amsterdam criteria for HNPCC. hMSH6 mutations have also been linked to endometrial cancer and the development of endometrial carcinomas.Wikipedia