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i5010570(D;I)

From SNPedia

likely to be BRCA2 variant pathogenic for breast cancer
is agenotype
ofI5010570
mentionedby
Magnitude6
ReputeBad
Geno Mag Summary
(D;D) 0 normal
(D;I) 6 likely to be BRCA2 variant pathogenic for breast cancer

Although named differently by 23andMe, this SNP represents rs397507419, a BRCA2 gene mutation pathogenic for breast cancer.

However we've had at least one case of this being in the 23andMe data, but not replicating when validated with a clinical test. Information about that case is visible at https://www.reddit.com/r/23andme/comments/53ay25/23andme_raw_data_accuracy_promethease_analysis/

If this occurs in your promethease report info@promethease.com would very much like to hear from you. We also suggest clinically validated testing to confirm.