(Redirected from I5010203(A;C))
- More frequent and more intensive screening for breast and ovarian cancer is recommended starting at perhaps age 25; however, screening has not been shown to reduce breast cancer incidence.
- Prophylactic surgery (e.g. bilateral mastectomy or salpingo-oophorectomy) has been shown to substantially reduce the risk for, as well as mortality from, breast or ovarian cancer in both high-risk women and those who are BRCA mutation carriers.
- Genetic counseling and/or testing is recommended for first-degree relatives as well as the same surveillance as carriers.
The full ClinGen Actionability report about Hereditary Breast and Ovarian Cancer can be found here.