i3003626

Gene (via rs)

Gene

Chromosome

3

Position

46414947

alias

Rs_StabilizedOrientation

plus

RsGeno	Mag	Summary
(-;-)	4	very resistant to HIV
(-;GTCAGTATCAATTCTGGAAGAATTTCCAGACA)	2	resistant to HIV
(GTCAGTATCAATTCTGGAAGAATTTCCAGACA;GTCAGTATCAATTCTGGAAGAATTTCCAGACA)	0	common form

The public name for this SNP is rs333, and it is most commonly known as the CCR5 Delta32 (or 'Delta 32') mutation.

It is discussed in numerous articles and blogs, including here and here.

II +/+: Not resistant to HIV infection; shows average time of progression to AIDS after infection.

DI Delta32/+: Not resistant to HIV infection but may have slower progression to AIDS after infection.

DD Delta32/Delta32: Resistant to infection by the most common strain of HIV people usually encounter, though protection is not complete.