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Haplogroup I (Y-DNA)

From SNPedia
Haplogroup I
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Haplogroup I (Y-DNA) is a Y chromosome clade. A clade represents all the branches - and thus descendants - of an taxonomic (or ancestral) tree that share a single common ancestor.Wikipedia

Y-DNA Haplogroup I represents one of the twenty major branches of the Y chromosome as defined by the Y Chromosome Consortium (YCC2008). Nearly one out of five Europeans is a member. Haplogroup I probably arose in Europe because it is almost non-existent outside of Europe.

Y-DNA Haplogroup I represents one of two major European Y chromosome haplogroups (the other major haplogroup is Y Haplogroup R). Unlike R, clade I is widespread in Europe and is virtually absent elsewhere. Subclade Haplogroup I1 (Y-DNA)) is found mostly in Northern Europe, while subclade Haplogroup I2 (Y-DNA) is the most frequent haplogroup in Eastern Europe and the Balkans.[PMID 18385274]

A study of 3,000+ British men concluded that carriers of haplogroup I had about a 50% higher age-adjusted risk of coronary artery disease than did men with other Y haplogroups (for the combined populations, with an odds ratio of 1.56, CI:1.24—1.97, p=0·0002). The association between haplogroup I and coronary artery disease was independent of traditional cardiovascular and socioeconomic risk factors.[PMID 22325189] However 23andMe disputes the link to coronary artery disease.

Haplogroup I (Y-DNA) SNPs[edit]

Haplogroup I (Y-DNA) defining mutations with rsIDs below, from ISOGG 2017 (version 12.213 10th August 2017).

- Note 1ː the same SNP is in Haplogroup J (Y-DNA) as L147.1 derived haplogroup J1a2a1a2b. Note 2ː the same SNP is in Haplogroup I (Y-DNA) as L147.3 derived haplogroup I2a2a1b2b,

- Noteː the same SNP is in Haplogroup N (Y-DNA) as P195.1 derived haplogroup NO1 (K2a),

- Noteː the same SNP is in Haplogroup D (Y-DNA) as M359.1 & P41.1 derived haplogroup D1b.

- Noteː the same SNP is in Haplogroup A (Y-DNA) as PF3627.1 & V218.1 derived haplogroup A1b1a1a2a1a~.


This haplogroup is defined in genoset Gs196.

P19 is not a SNP but a set of multiple mutations in DYS190.