Have questions? Visit https://www.reddit.com/r/SNPedia

HLA-DRB3

From SNPedia
is agene
is mentioned by
Full namemajor histocompatibility complex, class II, DR beta 3
EntrezGene3125
PheGenI3125
VariationViewer3125
ClinVarHLA-DRB3
GeneCardsHLA-DRB3
dbSNP3125
DiseasesHLA-DRB3
SADR3125
HugeNav3125
wikipediaHLA-DRB3
googleHLA-DRB3
gopubmedHLA-DRB3
EVSHLA-DRB3
HEFalMpHLA-DRB3
MyGene2HLA-DRB3
23andMeHLA-DRB3
UniProtP79483
OMIM612735
# SNPs1
 Max MagnitudeChromosome positionSummary
rs215733732,533,367


This gene is the major histocompatibility complex, class II, DR beta 3. It plays a central role in the immune system by presenting peptides derived from extracellular proteins.

According to OMIM 612735, HLA-DRB3 is also known as HLA-DR52.

[PMID 22654557OA-icon.png] The DRB3 gene has 3 major alleles: DRB3*0101 (DR52a), DRB3*0202 (DR52b), and DRB3*0301 (DR52c) (5, 6), with allele frequencies 0.073, 0.136, and 0.120, respectively.

The SNP variants within this gene are listed on the DRB3 page of UniProt. (Scroll down their page.)