|Summary||NAT2 Rapid metabolizer.|
This is ostensibly the "normal" type of metabolizer, who carries two rapid (active) acetylator alleles such as NAT2*4. NAT2 rapid acetylators can be typically be administered drugs which are substrates of the NAT2 enzyme following standard dosing practices.
This prediction and that of gs154 of NAT2 metabolizer phenotype is based on using 2 SNPs, rs1041983 and rs1801280.[PMID 21750470] An alternative prediction of NAT2 metabolizer status based on using more SNPs (6) is used by genosets gs138, gs139, and gs140.