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DRD2

From SNPedia
is agene
is mentioned by
Full namedopamine receptor D2
EntrezGene1813
PheGenI1813
VariationViewer1813
ClinVarDRD2
GeneCardsDRD2
dbSNP1813
DiseasesDRD2
SADR1813
HugeNav1813
wikipediaDRD2
googleDRD2
gopubmedDRD2
EVSDRD2
HEFalMpDRD2
MyGene2DRD2
23andMeDRD2
UniProtP14416
EnsemblENSG00000149295
OMIM126450
# SNPs37
 Max MagnitudeChromosome positionSummary
rs1048942200113,416,935
rs10765602113,412,966
rs10765620113,425,286
rs10795960113,425,897
rs10795970113,425,564
rs1079598113,425,552
rs10797270113,418,460
rs112146060113,439,147
rs112146130113,464,537
rs11244930113,411,573
rs11253940113,426,463
rs123631250113,415,194
rs123642830113,476,233
rs15549290113,408,042
rs176016120113,447,023
rs17997322113,475,529
rs17999780113,475,629
rs18004960113,412,766
rs1800498113,420,866
rs18010280113,412,762
rs20756520113,424,176
rs22346890113,407,761
rs22425920113,408,708
rs22832650113,414,814
rs27348390113,415,768
rs27348410113,411,054
rs27348420113,409,552
rs44365780113,436,043
rs46483171.2113,460,810
rs46483180113,442,667
rs46483190113,443,641
rs49380190113,470,669
rs62750113,412,755
rs62760113,410,675
rs62772113,412,737
rs62790113,410,351
rs71310560113,459,052

DRD2 encodes the Dopamine receptor D2, a target of various psychotropic agents, connected to memory and behavior.

SNPs in include:

[PMID 18063800] Genetically determined differences in learning from errors.

[1] Compared with DRD2 A1 carriers, subjects homozygous for the DRD2 A2 allele performed poorer in a measure of general cognitive functioning (MMSE) and in long term verbal memory. Our findings suggest that among the aged with cognitive impairments, the homozygous status for the A2 allele of the DRD2 Taq I polymorphism is associated with diminished cognitive performance and increased atrophy in the striatum.