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BDNF

From SNPedia
is agene
is mentioned by
Full namebrain-derived neurotrophic factor
EntrezGene627
PheGenI627
VariationViewer627
ClinVarBDNF
GeneCardsBDNF
dbSNP627
DiseasesBDNF
SADR627
HugeNav627
wikipediaBDNF
googleBDNF
gopubmedBDNF
EVSBDNF
HEFalMpBDNF
MyGene2BDNF
23andMeBDNF
UniProtP23560
EnsemblENSG00000176697
OMIM113505
# SNPs31
 Max MagnitudeChromosome positionSummary
rs10767664027,704,439
rs10835210027,674,363
rs1103009927,656,036
rs1103010027,656,039
rs11030101027,659,197
rs1103010327,660,786
rs11030104027,662,970
rs11030107027,673,288
rs11030119027,706,555
rs12273363027,723,312
rs12273539027,661,764
rs12291063027,672,554
rs13306221027,701,142
rs16917234027,676,827
rs16917237027,680,836
rs2030323027,706,992
rs2030324027,705,368
rs2049045027,672,694
rs2049046027,702,228
rs2872215127,659,629
rs41282918027,657,233
rs56164415027,700,188
rs6188880027,700,731
rs62652.627,658,369
rs7103411027,678,578
rs7103873027,678,770
rs7124442027,655,494
rs7127507027,693,337
rs8192466427,658,560
rs962369027,712,873
rs988748027,703,198

rs6265 in this gene has been linked to Alzheimer's disease.

[PMID 18518926] rs6265 aka Val66Met may influence general cognitive ability

[PMID 19018231] A study of 1749 Caucasian Americans from 250 multiplex bipolar families found evidence of association between several BDNF SNPs and risk of bipolar disorder

news SIRT1 seems to prevent a decline in levels of BDNF. People with Huntington disease tend to have low levels of BDNF.