The BAIAP2 gene on chromosome 17 encodes the insulin receptor tyrosine kinase substrate protein of 53 kDa (IRSp53).
A 2016 review and meta-analysis of genetic, pharmacogenetic and biochemical studies on ADHD in adults concluded that an association was seen for the BAIAP2 gene, but no other genetic, pharmacogenetic or biochemical association was found to be significantly associated. The association between adult ADHD and several variants in the BAIAP2 gene was not observed in children.[PMID 27217152]
The variants reported as being statistically significant were: