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ADAM33

From SNPedia
is agene
is mentioned by
EntrezGene80332
PheGenI80332
VariationViewer80332
ClinVarADAM33
GeneCardsADAM33
dbSNP80332
DiseasesADAM33
SADR80332
HugeNav80332
wikipediaADAM33
googleADAM33
gopubmedADAM33
EVSADAM33
HEFalMpADAM33
MyGene2ADAM33
23andMeADAM33
# SNPs22
 Max MagnitudeChromosome positionSummary
rs228008903,669,480
rs228009003,669,558
rs228009103,669,587
rs278709303,667,815
rs27870943,668,514
rs285320903,670,825
rs39183913,675,071
rs391839203,674,572
rs391839603,671,118
rs415348473,673,835
rs4470703,670,579
rs51189803,674,438
rs51262503,667,731
rs52855703,671,095
rs5437492.13,669,032
rs57417403,670,047
rs5979803,670,518
rs61270903,671,560
rs6154363,672,188
rs6289773,669,074
rs67704403,668,784
rs67888103,669,156


SNPs in the ADAM33 gene have been linked to a predisposition to asthma and bronchial hyperresponsiveness. [PMID 12110844, PMID 14564349]

These SNPs include:

At an individual level, another study [PMID 16773130] has found no association between any individual ADAM33 SNP and asthma predisposition, but they did find an association with ADAM33 haplotypes, leading to the conclusion that either some ADAM33 SNPs or SNPs in another gene located nearby are associated with asthma.

SNPs in the ADAM33 gene have also been linked to increased risk for chronic obstructive pulmonary disease among those who choose to smoke. The most significant of these ADAM33 SNPs are: