Know any genomes at Twitter support? Contact us if you can help get their attention.
If you think you've found an article that should be included, but don't feel capable of summarizing, please add it to the top of this list.
If you'd like to help, but don't know how... make anything here better.
- For some of those blank PMIDs at the bottom just click thru, copy their title. click edit, then paste next to the PMID.
- look at the most requested pages
If anyone is interested in expanding this list or some of the other P450 (CYP) enzymes, this page is quite a bit dated but still has a wealth of information: http://www.cypalleles.ki.se/ --McJosh (talk) 21:38, 3 November 2012 (UTC)
Mitochondrial snp database http://www.mitomap.org/cgi-bin/tbl9gen.pl
Interesting snp based statistical method [PMID 17564963]
http://www.ncbi.nlm.nih.gov/pubmed/18834360 What do we know about the genetics of aspirin intolerance?
The authors of A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans (doi:10.1038/nn1945), http://henry.simon.net.nz/stories/2007/08/01/the-genetics-of-traumatic-memories-adra2%ce%b2-and-rwandan-refugees/
http://www.eurekalert.org/pub_releases/2007-08/niom-sof072407.php antidepressant citalopram predicted by gene variation
[PMID 17545304] Tagging SNP haplotype analysis of the secretory PLA2-V gene, PLA2G5, shows strong association with LDL and oxLDL levels, suggesting functional distinction from sPLA2-IIA: results from the UDACS study.
[PMID 17640790] The A644G single nucleotide polymorphism (SNP) within intron 13 of the monoamine oxidase B (MAOB) gene is associated with successful short term (6 week) antidepressant treatment response in females (but not males). Female patients homozygous for the A-allele had a significantly faster and more pronounced antidepressant treatment response than AG or GG-carriers for paroxetine; differences for mirtazapine were similar but not statistically significant.
Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma.
[PMID 17460171] PECAM-1/CD31 in infarction and longevity.
this pdf from bioblogs #11 is about personalized genomics, and is a good general introduction.
Forbes does some coverage June 2007 including
blog post Eye on DNA from has too much info for me to digest
Arthritis (RA in particular) associated SNPs
Organ rejection/GVH disease, example: VEGF -1154 wrt renal transplants [PMID 11752046]
Silent mutations, which have important effects 
[PMID 17325707] An early acute reaction to radiation and/or the inheritance of the transforming growth factor-beta1 (TGFbeta1 -509T) SNP contributed to the risk of fibrosis. In contrast, an additional 15 Gy electron boost and/or the inheritance of X-ray repair cross-complementing 1 (XRCC1) (R399Q) SNP contributed to the risk of telangiectasia. A combined analysis of two UK breast cancer patient studies shows that 8% of patients are homozygous (TT) for the TGFbeta1 (C-509T) variant allele and have a 15-fold increased risk of fibrosis following radiotherapy compared with (CC) homozygotes.
[PMID 17334513] The -11377 C > G adiponectin gene promoter variant is i) associated with decreased serum adiponectin levels, ii) correlated with the presence of coronary atherosclerosis and iii) significantly predictive of vascular events among men undergoing coronary angiography.
[PMID 17088082] Genetic associations in preterm birth: a primer of marker selection, study design, and data analysis.
SNPs in the lymphotoxin-alpha conferred susceptibility to MI [PMID 17071996]
A snp that prevents feeling pain
osteoporotic vertebral fractures in postmenopausal women
- [PMID 17118999] Identification of an aromatase haplotype that is associated with gene expression and postmenopausal osteoporosis.
Neural-tube defects (Birth defects)
Allergic bronchopulmonary aspergillosis (ABPA) (Asthma related)
rapid lung function decline
choice of chemotherapy
meningococcal disease susceptibility
recurrent venous thromboembolism
A snp to control early wake/sleep cycles
Liver transplant outcomes
SSRI treatment efficacy
High-Density Lipoprotein-Cholesterol and Overweight
kidney allograft transplantation
H. pylori infection and chronic gastritis
Just too busy
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- [PMID 16614108] [] was significantly associated with an increased risk of breast cancer
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Stone and his colleague, Dr. Val Sheffield, decided the only way their research findings could help patients would be for them to create and offer genetic tests to primary-care physicians
Their goal is to develop a clinically useful test for every eye disease that has a known genetic connection.
However, getting into the testing business, even on a non-profit basis, presents challenges that can be daunting.
Dr. Stone's university-based testing laboratory, operating with a $5 million grant from the Carver family of Muscatine, Iowa, charges patients only for materials and technician time needed to perform tests. Stone tries to get those costs below $500 per test rather than the thousands it typically costs to do such work in a research setting.